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Inappropriate Treatment of Lymphoma
by: DR SOON
Most of us have heard of leukaemia. But not many of us know what is a lymphoma. This article is about the treatment of lymphoma. Generally it is very difficult and frustrating to treat lymphoma. Most doctors do not know how much about the treatment of lymphoma. Only one aspect is emphasized here. That is, lymphoma is commonly under treated. Failure of treatment of lymphoma is often due to under treatment.

This article is written for doctors and some lymphoma patients only. If you are not a doctor there is no point reading further.

Lymphoma is generally classified into Hodgkin and non-Hodgkin lymphoma. The behaviour of lymphoma changes with the age of the patient. The older patient modulates tumour growth differently. For example, the concentration of interleukin-6 (IL-6) in the circulation increases with age. As IL-6 stimulates lymphoproliferation, the prognosis of Non-Hodgkin's Lymphoma (NHL) worsens with age.

Groshan Fabiola has written a number of good articles on lymphoma. I agreed with what he said. This article is meant to re-emphasize what he said for the education of doctors.

The clinical intervention of lymphoma generally uses a wide variety of immunosuppressant medications and a series of specific cancer therapies. Patients with lymphoma are often prescribed combination treatments, receiving carefully established doses of cancer medications according to age, gender and more important, the type of lymphoma and its stage of progression. In order to maximize the potency of the treatment and reduce the risks of relapse, doctors need to take into consideration all these previously mentioned proven facts and variables when deciding upon the appropriate dose of medications.

If wrong dosage are administered, the treatment will either fail to accomplish its expected action (in case of under-dosage) or generate severe temporary or even permanent side-effects (in case of over-dosage). Choosing the most appropriate drugs and deciding the perfect individual dose for each patient with lymphoma is a very challenging and time-consuming task for doctors. However, if this protocol is not followed correctly, the existing treatment of lymphoma can produce a series of undesired results.

Recent medical research have revealed that the under-treatment of lymphoma is a very common phenomenon in hospitals, clinics and other medical establishments worldwide. Many lymphoma patients had relapses The cause has been recently identified as due to under-treatment. Owing to the fact that repeated treatments often fail to control the progression of lymphoma in relapsed cases, it is very important to plan the treatment in great detail. Doctors have to establish the appropriate dose of medications and decide upon the right duration for a particular case. Although the doses of lymphoma medications can be slightly adjusted over the period of administration, under-treatment of lymphoma should be avoided at all costs.

According to oncologists, patients who suffer from aggressively progressing Non-Hodgkin's Lymphoma (NHL) should receive the specific chemotherapeutic treatment in precise doses and without delay in order to prevent relapse. Although rapidly progressing Non-Hodgkin's Lymphoma is considered to be a severe, life-threatening disease, the existing forms of treatment and therapies can successfully reverse the malignant effects of the lymphoma cancer on the body and slow down the progression rate of the disease.

Paradoxically, fast progressing Non-Hodgkin's Lymphoma subtypes, as well as Hodgkin's Lymphoma are more curable than slower progressing lymphomas. The phenomenon is partially  explained by the increased drug potency of existing chemotherapy in fighting against rapidly dividing malignant cells. However, despite the high curability of these varieties of lymphoma, it is imperative to prescribe the specific course of treatment in the right doses in order to obtain the best results. If the treatment is delayed, prematurely stopped or prescribed in the wrong doses, the risks of relapse are considerably increased and the afflicted patients rarely respond to re-treatment.

Recent studies conducted in randomly chosen medical establishments nationwide have revealed very disturbing facts regarding the treatment of lymphoma patients: around 50 percent of patients with highly curable forms of lymphoma cancers receive considerable dose reductions during chemotherapy. Thus, the chances of long-term survival for this category of patients are substantially reduced, despite the curable nature of their disease. Researchers have stated that it is imperative for oncologists to avoid under-treatment for patients with curable forms of lymphoma and that future treatments should be optimized in order to minimize the risks of relapse.

Doctors must be aggressive in their approach to prevent under treatment while monitoring the side effects to prevent over dosage at all times. The initially decided doses of medications should not be reduced unless the patients with lymphoma are confronted with severe side-effects. According to medical researchers, less than 5 percent of all lymphoma cases actually require ulterior changes in dosage; the other 95 percent of cases should receive the specific treatment in the same dose until the disease is completely overcome.
 

If you have questions related to this article you may e-mail me at doctor@soontongkiong.com quoting the contents of the article.

About the author

DR SOON is a medical practitioner. He holds four degrees. MBBS (University of Malaya), MBA (University of East Asia), LLB (Hons) (University of Wolverhampton), Master of Medicine (Edith Cowan University

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Dr SOON is the owner of AskMyVisitor.com and  MyScriptDoctor.com

where you can find the most up-to-date advice and information on

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