| Patients with
cancer of cervix commonly had primary irradiation therapy. Some
patients are cured but others develop some form of complications.
One such condition is central pelvic recurrence. This clinical
condition is a life threatening situation. When such treatment
follows stage 1 or 2 disease, then it is possible to offer a
chance of cure through ultra radical salvage surgery such as
pelvic exenteration. Cure rates range from 26 to 60 % but depend
very much on patient selection.
Extended or ultraradical surgery in the treatment of advanced
pelvic cancer is an American innovation made possible by advances
in the ancillary sciences. The natural history of many pelvic
cancers is that they may be locally advanced yet still limited to
the pelvis. They are therefore potentially resectable. Pelvic
exenteration were first intrioduced by Brunschwig and Pierce in
1948. However, they were subjected to severe criticism. Today,
this procedure has attained an important role in the treatment of
gynaecologic cancers, offering the potential for cure to selected
patients for whom no other alternatives exist. Furthermore it has
been shown that patients who survive this procedure can be
rehabilitated to a useful and meaningful life.
Total exenteration with removal of the
pelvic viscera including the bladder and the rectosigmoid is the
procedure of choice for advamced cancer of cervix within the
pelvis after irradiation. In selected cases the the procedure may
be limited to either anterior exenteration or posterior
exenteration.
Only those patients with centrally
recurrent cancer are suitable for pelvic exenteration. Metastasis
outside the pelvis are considered absolute contraindications. The
combined triad of unilateral leg oedema, sciatic pain, and
ureteral obstruction is pathotgnomonic of recurrent and
unresectable disease in the pelvis. Weight loss, cough, anaemia
and other complaints suggestive of advanced disease are not
sufficient justification to exclude surgical management.
If you have questions related to this article you may e-mail me
at doctor@soontongkiong.com quoting the contents of the article.
About the author
DR SOON is a medical practitioner. He holds four degrees. MBBS
(University of Malaya), MBA (University of East Asia), LLB (Hons)
(University of Wolverhampton), Master of Medicine (Edith Cowan
University
:
Dr SOON is the owner of AskMyVisitor.com and MyScriptDoctor.com
where you can find the most up-to-date advice and information
on
many medical, health and lifestyle topics.
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